In contrast, in the animal model of sepsis-induced ALI, different statins attenuated inflammatory injury and apoptosis in pulmonary parenchyma, enhanced antioxidant enzymes, and improved endothelial permeability and the level of junction proteins through regulating different pathways, such as Cav-1/eNOS or TLR4/NF-kB [14,15,18,27]. The gene discussed is CAV1; the disease is Sepsis.