NFKB1 and acute kidney injury: NFkB is one of the most studied transcription factors that, after activation, is translocated to the nucleus where it governs a pro-inflammatory response during AKI in many different cells, for instance, it regulates the expression of adhesion molecules such as VECAM in endothelium [49], the expression of cytokines and apoptosis in tubular epithelial cells and monocytes [50], and regulates the population of lymphocytes after renal IR [51].