Further, three identified proteins were reported to be associated with osteoblastic diseases: while Stathmin 1 (STMN1) was described for osteoblast and osteoclast function [61] as well as for osteopenic phenotypes in mice [62], we found minichromosome maintenance complex component 4 (MCM4) which seems to play an important role during cell division and metastasis-free survival of osteosarcoma patients [63]. Here, MCM4 is linked to osteosarcoma.