PROM1 and chronic kidney disease: We evaluated the effects of EVs (exosomes and microvesicles) from human umbilical cord tissue (hUCT)-derived mesenchymal stem cells (MSCs) and expanded human umbilical cord blood (hUCB)-derived CD133+ cells (eCD133+) on 30 Wistar rats with CKD induced by excess dietary adenine (ADE).