Figure 2 illustrates stem cell marker expression in sulindac sensitive (SUL-S) and sulindac resistant (SUL-R) cells isolated from the parental 850 MIN COL cells. Stem cell markers tumor spheroids (TS), CD44, CD133 and c-Myc represent established cellular and molecular markers for stem cells [19,21,22]. The gene discussed is MYC; the disease is neoplasm.