With the help of prospectively collected serum samples, the scope of the present study was to simultaneously evaluate the antibody response to the most relevant antigens in CeD, namely, non-deamidated gliadin peptides (NGP), deamidated gliadin peptides (DGP) and TG2, and its evolution over time in children consuming gluten regularly from foods in both groups after 6 months of age. Here, TGM2 is linked to cranioectodermal dysplasia.