In addition, HIF-1α, together with IL-6, vascular endothelial growth factor (VEGF), microRNA-150, microRNA-270, ROS, bone morphogenetic protein 6 (BMP6), triggering receptor expressed on myeloid cells 1 (TREM-1), and PI3K/protein kinase B (AKT) signaling pathway, is involved in psoriasis pathogenesis [56]. The gene discussed is BMP6; the disease is psoriasis.