In amygdala, the overall piRNAs-aligned pseudogenes ratio is not different in Parkinson’s disease (Figure 9b), but some related pseudogene-aligned piRNAs, including HSP90, MTCO1, MTCO2, YWHAZ, GAPDH, and MTND were upregulated in the PD group. The gene discussed is MT-CO1; the disease is Parkinson disease.