From the Parkinson’s disease KEGG enrichment result, five of differently expressed piRNAs-aligned genes (NDUFA4, CALM3, UCHL1, CALM2, and HSPA5) in the prefrontal cortex (15 genes) overlapped with differently expressed piRNAs-aligned genes in the amygdala (16 genes). The gene discussed is HSPA5; the disease is Parkinson disease.