From considerations of metabolic modeling of MG metabolism and potency of the active Glo1 inhibitor, S-p-bromobenzylglutathione (BBG), delivered into cells by BBGD, we predicted that to achieve potent inhibition of tumor cell growth, the cellular concentration of MG was increased over 12-fold for ca. 24 h of the cell growth cycle [19]. Here, GLO1 is linked to neoplasm.