CCL2 and infection: As an example, the chemokines CCL1, CCL2, CXCL2, and CX3CL1 play a significant role in the pathogenesis of the coronary heart disease [34,35]; CCL2, CCL5, CCL7, and CXCL1 have a role in acute myocardial ischemia [36,37,38]; and CCL2, CCL5, CXCL9, and CXCL10 are significant in the response to an infection (examined on the model of Trypanosoma cruzi infection) [39,40].