VCP and amyotrophic lateral sclerosis: Point mutations in superoxide dismutase 1 (SOD1, 20% of all fALS) and expanded GGGGCC repeats in C9orf72 are the most frequent ALS genes, whereas mutations in TAR deoxyribonucleic acid (DNA) binding protein 43 (TARDBP), fused in sarcoma/translocated in liposarcoma (FUS/TLS), TANK-binding kinase 1 (TBK1) or valosin-containing protein (VCP) account for less common genetic causes [16,17].