KCNQ2 (OMIM 602235)-associated seizures typically occur in the first week from birth and can contribute to benign familial neonatal convulsions (BFNCs), benign familial infantile seizures [1,2,3,4,5], and neonatal-onset epileptic encephalopathy (EE) [6,7,8]. The gene discussed is KCNQ2; the disease is ethylmalonic encephalopathy.