TPP1 and pulmonary fibrosis: Corresponding to the β-turn hairpin-like blade 7 of FBW7 E3 ubiquitin ligase WD40 domain, as synthesized in a native or retro-inverso (reversed, inversed in dextral amino acids) configuration, TELODIN competitively inhibited stress-induced TPP1 accelerated turnover, telomere shortening and pulmonary fibrosis once applied through intratracheal instillation in mice [35,213].