Similar to what was observed in the control group with abdominal obesity, we identified a significant decrease in the GF in PCOS women compared to the ABD depot of genes related to lipid metabolism (LPL, CD36, SNAIL and ADIPOQ; Figure S2A), angiogenesis (VEGFα, RSPO3; Figure S2B) and perturbation of genes involved in ECM remodeling (FN1, COL6A1 and MMP3; Figure S2C). The gene discussed is RSPO3; the disease is Abdominal obesity.