Interestingly, the telomerase reverse transcriptase overexpression in transgenic mice (Sp53/Sp16/SArf/Tg Tert mice) showed improved tumour resistance and was found to prevent ageing-related degeneration (mainly atrophy) and inflammatory processes, higher blood levels of IGF1, and a reduction in γ-H2AX foci. Here, TERT is linked to neoplasm.