Gene expression modulation of BER and EGF signaling was assayed in starved human thyroid follicular epithelial Nthy-ori 3-1 cells and starved papillary carcinoma cell line TPC-1 after short term treatments (15 and 30 min), with H2O2 [10 mM], EGF, PD, LY alone or combined. This evidence concerns the gene EGF and thyroid gland papillary carcinoma.