RBP1 expression is reduced in many of the most prevalent cancers including breast, prostate, lung, colon and rectal, melanoma, bladder, non-Hodgkin lymphoma, leukemia, endometrial, and pancreatic cancer [17,18,19,20,21,22,23,24,25,26]. The gene discussed is RBP1; the disease is familial pancreatic carcinoma.