SIRT1 and cyclic hematopoiesis: circ-SIRT1 deficiency was conducive to CH formation, and the overexpression circ-SIRT1 elevates SIRT1 expression by competitively binding with miR-3681-3p/miR-5195-3p or recruits USP22 to stabilize SIRT1 protein in hiPSCCMs [103].