Despite a significant correlation between the expression of PDE2A and MIR139 in lung cancer cell lines [40], we and other investigators have shown that miR-139-5p and/or miR-139-3p expression is not correlated to PDE2A expression levels in leukemia [38], gastric [41] and colorectal cancer cells [42]. The gene discussed is PDE2A; the disease is lung carcinoma.