QX decreased Col I and α-SMA in lung tissues via the inhibition of TGF-β1-Smad2/3 signaling, suppressed EMT, and effectively reversed abnormal mRNA expression of MMP-1, TIMP-1, and LOXL-2 in the lung tissues of BLM-induced PF mice [217]. The gene discussed is TGFB1; the disease is pemphigus foliaceus.