Bleomycin (BLM)-induced IL-17A formation is also strongly focused on TGF-β1 sensing, and recombinant IL-17A-induced fibrosis is based on TGF-β1-downstream profibrotic involvement, implying that IL-17A and TGF-β1 perform a cooperative feature in the progression of PF [44]. This evidence concerns the gene TGFB1 and pemphigus foliaceus.