The gene expression analysis according to severity (Figure 1B) showed that all the patient groups had higher MSR1 gene expression than the C. Severe NA (RQ = 3.05, p = 0.0162), moderate–mild NA (RQ = 3.65, p = 0.0005), moderate–mild AA (RQ = 5.47, p = 0.0008), and severe COPD (RQ = 3.64, p = 0.0022) followed our statistical criteria (RQ > 2, p < 0.05) and the difference between the C and severe AA groups was statistically significant (p = 0.0378), but with a lower RQ value (RQ = 1.94). The gene discussed is MSR1; the disease is chronic obstructive pulmonary disease.