In addition, other metabolic pathways that would explain the association between prediabetes and OSA have also been suggested, such as microvascular damage, lung microangiopathy, decreased muscle strength, nonenzymatic glycosylation of lung proteins, defects in the bronchiolar surfactant layer and the deficit in glucagon-like peptide 1 concentrations [1]. The gene discussed is GCG; the disease is obstructive sleep apnea syndrome.