In addition, other metabolic pathways that would explain the association between prediabetes and OSA have also been suggested, such as microvascular damage, lung microangiopathy, decreased muscle strength, nonenzymatic glycosylation of lung proteins, defects in the bronchiolar surfactant layer and the deficit in glucagon-like peptide 1 concentrations [1]. This evidence concerns the gene GCG and prediabetes syndrome.