Fabry disease (FD, OMIM #301500) is an X-linked disorder characterized by defects in the alpha-galactosidase A enzyme activity that lead to the ubiquitous accumulation of glycosphingolipids, mainly globotriaosylceramide (Gb3) and globotriaosylsphingosine (lysoGb3). Here, GLA is linked to Fabry disease.