Moreover, some research also suggested that an imbalance of cytokines can induce brain damage [25] i.e., the number of proinflammatory cytokines like interleukin-6 (IL-6), interleukin-8 (IL-8), and tumor necrosis factors (TNC) are significantly increased after therapy for malignant tumors [26]. The gene discussed is CXCL8; the disease is cancer.