ELD-AR category genes enriched in pathways mainly related to “organismal systems (digestive system)”, “metabolism (lipid, vitamins, xenobiotics metabolism)”, and “diseases (cancer, drug resistance, neurodegenerative diseases)” (Figure 9B), including, for example, 13 genes involved in “bile secretion”, 7 genes involved in “metabolism of xenobiotics by cytochrome P450”, 10 genes involved in “steroid hormone biosynthesis”, and 10 genes involved in “platinum drug resistance” (Figure 10B). The gene discussed is ARID1A; the disease is cancer.