The results of RT-qPCR (Figure 8e–j) showed that the expressions of TNF-α mRNA, IFN-γ mRNA, IL-13 mRNA, NF-κB mRNA, IkBα mRNA, and Ikkβ mRNA in the BLM-induced rats increased significantly compared to those in the normal group, while their expression levels were downregulated obviously by TRF and carotene. This evidence concerns the gene NFKBIA and Bloom syndrome.