However, the inverse effect was observed after HFD treatment as PRKACA, CCT3, and GLUD1 expression increased (1.240 FC; p = 0.0064, 1.622 FC; p = 0.0087, and 1.297 FC; p = 0.0118, respectively) and MYL6 expression decreased (−1.631 FC, p = 0.0167) compared to expression in the SCD group. The gene discussed is PRKACA; the disease is Schnyder corneal dystrophy.