These results are consistent with those of Keyhani-Nejah et al. [33], who reported in a randomized crossover study with 35 subjects (15 healthy, 10 prediabetic, and 10 T2DM) that the ingestion of 50 g of CH from isomaltulose produced significantly lower peaks of glucose and insulin, along with a lower AUC of GIP. The gene discussed is INS; the disease is type 2 diabetes mellitus.