PTH and Acidosis: Acidosis resulted in a decrease in plasma PTH in all groups, 96.5 ± 22.3 vs. 107.3 ± 19.1 pg/mL, 113.1 ± 17.3 vs. 185.8 ±22.2 pg/mL and 504.9 ± 75.7 vs. 1255.4 ± 181.1 pg/mL, although significant differences were only observed in rats with reduced renal function (Figure 3).