Gastrocnemius muscle aldehyde dehydrogenase 2 (ALDH2) protein expression was significantly lower in mice fed both a LF + EtOH diet (0.34-fold, p = 0.045) and a HF + EtOH diet (0.30-fold, p = 0.03) relative to EtOH-free HF diet (Figure 5A,B). The gene discussed is ALDH2; the disease is hydrops fetalis.