Cofactors should be always investigated (e.g., asthma exacerbations, infections, exercise, alcohol, tiredness, use of NSAIDs, and menstruation), since they usually play a crucial role in eliciting reactions in patients allergic to nsLTP (Pru p 3 in peach) and, less frequently, in patients allergic to gibberellins (more evident for Pru m 7 (apricot) and Cit s 7 (orange) less for Pru p 7 (peach)). Here, SCP2 is linked to asthma.