Another study showed that AGEs may alter the enzymatic activity of specific enzymes such as cholesterol side-chain cleavage enzyme cytochrome P450, steroidogenic acute regulatory protein (StAR), 17α-hydroxylase, and 3β-hydroxysteroid dehydrogenase leading to the symptomatology of hyperandrogenism in PCOS [71]. The gene discussed is STAR; the disease is polycystic ovary syndrome.