A recent study has shown that knockdown of Baz1a by lentivirus-mediated short hairpin RNA (shRNA) induced senescence-associated phenotypes in various cells, such as A549 (a lung adenocarcinoma cell line), U2OS (human bone osteosarcoma epithelial cells), HUVEC (human umbilical vein endothelial cells), NIH3T3 (a murine embryonic fibroblast cell line), and MEF (mouse embryo fibroblasts) [37]. Here, BAZ1A is linked to lung adenocarcinoma.