The objectives of this study were: to determine the prevalence of the MHO phenotype in Arab and South Asian ethnic groups in Kuwait; to assess the differences between the phenotypes based on the definition of obesity (BMI vs. WC); and to assess the relationship between the MHO and MuHO, and hs-CRP, ALT, and insulin resistance, quantified using the homeostasis model assessment (HOMA). The gene discussed is GPT; the disease is Obesity.