Tau might be able to influence tumorigenesis by abnormal modulation of cell cycle progression, cell mobility, or organelle organization, and in fact, neurons from patients suffering from neurodegenerative diseases, including characteristic tau pathology, display hallmarks of DNA replication and active cell cycle as well as microtubule-mediated deformation of the nucleus [79,80,81]. The gene discussed is MAPT; the disease is neurodegenerative disease.