IDH2 and astrocytoma (excluding glioblastoma): Diagnosis can be obtained only using pathological tissue after a biopsy or resection [3,47] but hemodynamic imaging has also shown potential for the identification of IDH 1p/19q codeletion status as part of the differentiation of oligodendroglioma from the IDH mutant 1p/19q non-deleted astrocytomas and IDHwt glioblastomas [10,11,12,30,48].