ERBB2 and breast cancer: In contrast, the number of N-cadherin positive cells was unchanged when we stratified the tumours according to the presence of distant metastasis (Figure 6k) and PR and HER2 status (Figure 6l,m), while, when we stratified our samples for the ER status, a trend of increase in the N-cadherin-positive cells (p = 0.08) was found in the ER-positive compared to the ER-negative primary breast cancers (Figure 6n).