In addition, CaMKII has been implicated in the activation of multiple oncogenic signaling pathways, such as the MAPK, AKT/mTOR, JAK/STAT, GSK3β/β-catenin, Notch, and NF-κB pathways, which play a critical role in cancer progression [15,22,23,24]. Here, NFKB1 is linked to cancer.