SLC16A1 and telomere syndrome: However, the unadjusted p-values of these MCTs indicated a significant upregulation of SLC16A7 (logFC = 1.3) and downregulation of SLC16A1-AS1 (logFC = −1.0) in STS subjects (p-values of 0.003 and 0.006, respectively) (Figure 4).