These in vitro findings were then reconfirmed on human eBL samples by immunostaining (Figure 3d), showing weak TGFBI staining in 18/20 EBV(+) BL samples compared with BL(−) or healthy lymphoid tissue samples, suggesting the transformation status associated with EBV infection to reduce TGFBI protein expression in vivo. The gene discussed is TGFBI; the disease is Epstein-Barr virus infection.