MADD and cancer: By showing that hnRNP H/F switch the splicing of A-Raf mRNA in GBM (Figure 1), our results not only extend this splicing event to other cancer cells than head and neck and colon cancer cells [37], but also add A-Raf to the list of mRNAs spliced by hnRNP H in GBM (including the adaptor protein IG20/MADD and the RON receptor tyrosine kinase [32]) and assign a novel function for hnRNP F as a splicing regulator in GBM, which has not been reported so far.