Our results showing that hnRNP H depletion increased the expression of the exon5-containing eIF4H long isoform (Figure S3) raises questions of whether and how hnRNP H overexpression in GBM induces exon 5 splicing of eIF4H, generates miR-590 expression and contributes to GBM cell radioresistance. The gene discussed is EIF4H; the disease is glioblastoma.