CEACAM5 and neoplasm: Multivariate analysis of the four risk factors obtained from univariate analysis demonstrated that serum CEA level (≥5 ng/dL vs. <5 ng/dL, odds ratio (OR = 6.80, 95% confidence interval (CI) 1.89–24.40, p = 0.03), solid part diameter (≥1.3 cm vs. <1.3 cm, OR = 4.36, 95% CI 1.39–13.68, p = 0.012), C/T ratio (≥0.50 vs. <0.50, OR = 4.93, 95% CI 1.16–21.02, p = 0.031), and tumor location (central vs. peripheral location, OR = 4.64, 95% CI 1.84–11.70, p = 0.001) were independent and significant risk factors for nodal upstaging.