In a mouse model of colorectal cancer liver metastasis, colorectal cancer cells recruited CCR1+ myeloid cells (mostly granulocytic MDSC phenotype) by expressing CCL-9 to expand metastatic foci in the liver [18], and the enriched myeloid cells in metastatic foci included CCR1+ neutrophils, eosinophils monocytes, and fibrocytes [19]. This evidence concerns the gene CCR1 and colorectal cancer.