We have previously reviewed list of 78 female patients (age ≥ 18 years) who received genetic counseling at the Department of Medical Genetics, National Cancer Institute, Bratislava, Slovakia, during the period of 2009–2019 due to personal or family cancer history, who were found to be heterozygous carriers of either the p.I157T (N = 71) or the c.1100delC (N = 7) germline CHEK2 mutation. Here, CHEK2 is linked to cancer.