MITF and melanoma: To avoid confounding effects due to intrinsic cell heterogeneity within tumor samples, we analyzed the expression levels of Mitf, a key TF governing the state of melanocyte differentiation [49], the levels of which are related to the proliferative and invasive states of melanoma (reviewed in [11]), and a panel of EMT-TFs in the MeL3 cell line with or without Loxl3 expression.