We further evaluated the effects of CBD treatment on a panel of CSC markers and found that CBD downregulated protein expression of Snail, Nanog, and Vimentin were significantly in both H460 (Figure 4E,F and Figure S3) and A549 (Figure 4G,H and Figure S3) NSCLC cells, highlighting a role for CBD in downregulating stem cell properties in CR cells. This evidence concerns the gene VIM and non-small cell lung carcinoma.