BCR and metastatic neoplasm: Interestingly, Jansen et al. analyzed PSMA PET/CT performed in 63 patients with low PSA levels (<2.0 ng/mL, not meeting BCR criteria) after curative radiotherapy and found PSMA positive lesions in 53/63 patients (84.1%) defined as local recurrence (21 patients) or metastatic disease (32 patients) [43].