Transfer of a sulfate residue to GlcNAc residues in keratan sulfate by CHST2 has been revealed to activate the p38 MAPK-PI3K (mitogen-activated protein kinase/phosphatidylinositol 3-kinase) cell signaling pathway and decrease cell apoptosis caused by radiation in Burkitt’s lymphoma cells [54]. The gene discussed is WNK2; the disease is Burkitt lymphoma.