In HNSCC, miR-101-3p enriched exosomes derived from human bone marrow mesenchymal stem cells (hBMSCs) overexpressing miR-101-3p, were able to suppress oral cancer cell proliferation and tumor growth both in vitro and in vivo by targeting the Collagen Type X Alpha 1 Chain gene (COL10A1), resulting in downregulation of Collagen X expression [33]. The gene discussed is COL10A1; the disease is head and neck squamous cell carcinoma.