In HCC, nuclear and cytoplasmic STAT1 expression, together with the STAT1-positive immune cell infiltrate, correlated highly significant with CD3-, CD4-, CD8-, and FOXP3-positive immune cell infiltrates (Spearman r = 0.335, 0.349, 0.348, and 0.394, all with p < 0.001; Figure 4A,B and Supplementary Figure S3). This evidence concerns the gene CD4 and hepatocellular carcinoma.